Our Adoptable Kittens

Please see our adoptable kittens page to find your forever kitten.  These kittens need loving homes and they have lots of love to give in return.

Adoptable Kittens

Our Programs

Learn about all our programs to bring love to the upstate kitten population and become part of a movement


Support Our Work

About Miss Dixie's Kitten Rescue

Our Mission

We are a 501©3 nonprofit kitten rescue located in Seneca, South Carolina founded in 2019.

Our mission is to provide specialized care and attention to sick, injured and orphaned feline neonates and prepare them for placement into loving, forever homes.

  • Left to the elements, most orphaned kittens cannot survive on their own.
  • They need specialized care and medical attention in order to thrive.
  •  Our network of foster homes is dedicated to the rescue, rehabilitation and adoption of these kittens.

Learn more

Kittens taken into the rescue


Adopted into loving forever homes


of survival rate of kittens in care



Our Programs

We specialize in rehabilitating sick and injured kittens as well as raising orphaned neonatal felines. We are currently expanding our efforts to include a Full-Circle program focused on Trap, Neuter, Return (TNR) in the Upstate. Our #1 goal is to reduce the number of sick, injured, and orphaned kittens coming into shelters.

  • TNR Program
  • Foster/Adoption Program

Trap-Neuter-Return (TNR)

Kittens do not magically appear out of nowhere. Every kitten has a story, and that story generally leads us to a colony of cats.

Foster/Adoption Program

Miss Dixie’s Kitten Rescue is comprised of a network of foster homes dedicated to the health and wellbeing of every kitten in our care.

Opportunities to Sponsor

Like every non-profit we encounter everyday expenses that without supporters like you we could never do this work.

Donate - Join Miss Dixie's Kitten Crew

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Contact Us

Send us a Message

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Our Instagram


Lydia has been in our care for a very long time. Recently she was adopted to what was the perfect home, but sadly due to severe allergies, she must come back to the rescue. We and the adopter are devastated, but want to do what is best for everyone involved.

Lydia is an incredibly sweet, loving and affectionate cat. She adores human attention and wants it all for herself. Because of this, she does not do well with other cats and must be the only cat in the home.

Normally we require adopters to have another cat in the home, but Lydia is the exception. We are currently looking for either a foster to adopt or a foster home for Lydia as she makes her way back to the rescue.

🚨Please message us ASAP if you can help🚨

We love getting to say hi to the kitties we have previously TNR’d when we go back out to a colony. Midnight was TNR’d last year and is happy, healthy, and was rolling around enjoying the sun today. 🖤☀️ ...

POV: you adopted a rescue kitten and now you’re spending a lazy Saturday with them cuddled up with you on the couch. 💕 ...

💛Update on Ernesto, the injured kitty we needed an emergency foster for.💛

He is doing great in his foster home and his wound is healing nicely! His foster says he loves all the other cats in the house and he is super affectionate. He enjoys following them all around the house to spend time with them.

Fun fact: did you know polydactyl cats (cats with extra toes) are sometimes called Hemingway cats? This is because Ernest Hemingway loved and owned a polydactyl cat named Snow White. His home & museum is now home to around 60 polydactyl cats!

We are happy to share our 2022 impact numbers with you all today. As always, it is important to us to stress that we couldn’t do what we do without to support of our donors, volunteers, and fosters!

Because of you…

🚑We were able to rescue 166 kittens and cats this year!
🏠We placed 159 kittens into perfect, loving homes.
❤️‍🩹We had an over 99% survival rate, even with our focus being fragile, sick, neonatal kittens.
🐈‍⬛This year we launched our full-circle TNR program and TNR’d 177 cats! If just half of that number would have had only one litter of kittens this year, that would have been over 350 kittens born that we were able to prevent!

We are looking forward to making even more of an impact in 2023! Thank you!

🐱Have you ever thought about fostering kittens? As a foster-based rescue, we rely on foster homes to be able to save kittens and raise them until they are ready to be adopted into their forever homes. We are looking to add some more foster homes to our network! If you are interested, please fill out our foster application. We would prefer to have our foster homes in within a 30 minute radius of Seneca/Clemson. Fostering is extremely rewarding and fun! We couldn’t make the impact we do without all of our fosters!


Our kitten calendars should start shipping this week! We can’t wait for everyone to get them! There are still a limited number left if you haven’t gotten one yet. The link to order is in our bio. 💛 ...

Thank you to the @andersoncountylibrary for taking up donations to support us & @andersoncountypaws_sc! We received a huge load of towels, blankets, food, litter, and toys for the rescue and our TNR program. Thank you to everyone who donated something! And if you haven’t been to your local library in a while, this is your sign. 😉 ...

❄️With very low temperatures coming, especially lower than we are used to in the south, please consider these tips to provide some extra care to your outdoor cats or the community cats in your neighborhood.

🐈There are many great tutorial videos online on how to make an easy DIY cat shelter! Alley Cat Advocates has great step by step instructions here: https://alleycatadvocates.org/communitycat-care-center/creating-winter-shelters/

💙Stay safe everyone!